SpinChem®’s RBR unleash the full potential of INOFEA’s enzzen® technology
INOFEA’s unique and patented technology enzzen® let enzymes stand challenging conditions.
The use of enzymes is strongly limited by the fact that their structures are sensitive and fragile, like most proteins, and often not fitted to process conditions. Many expensive genetically engineered or biological enzymes show remarkable properties but still need to be made more robust for various applications.
The enzzen® technology allows the immobilization of any enzyme or cocktail of enzymes onto particles and their protection by growing a structured shield on the outer surface. The shield prevents the enzyme denaturation and provides a remarkable resistance to various process conditions, such as acidity, temperature, presence of chaotropic agents, proteases, etc.
The Rotating Bed Reactor (RBR) by SpinChem® offers huge advantages in both the preparation of enzzen® enzymes and their deployment in biocatalytic processes.
By implementing the RBR at INOFEA, we have reached a faster and cheaper process to produce immobilized and shielded enzymes through enzzen®.
In biocatalysis the benefit of RBR for enzzen® immobilized and shielded enzymes consists in an improvement of the mass transfer in heterogeneous catalysis and in the minimization the mechanical stress.
In conclusion the synergy of the RBR by SpinChem® and enzzen® by INOFEA express the best of both technologies leading to more efficient biocatalytic reactions, with clear benefits in reliability, safety, costs saving and environmental sustainability.